I've settled on a .44 with 4" barrel. I will be using Garrett's Defender round.
There's a really good deal here now on the Taurus Model 444 Ultralight Titanium. One of my co-workers just got one and the price is right, in addition to the lightness of the gun. I'm going to take my wife out to practice with some .44 special.
Anyone know of any issues with that Taurus? I haven't found much about it other than complaints about kick, which seems pretty universal for .44 anyway...

