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  1. #1
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    New "sex in a spray bottle" product to help woman's libido

    Billed as libido in an atomiser, PT-141 will finally offer women the chance to turn on their sexual desire as and when they need it. Or so the science says. But there are concerns. Will sex in a spray usher in an age of 'McNookie' - quick easy couplings low on emotional nutrition? Julian Dibbell reports

    Horn of rhinoceros. Penis of tiger. Root of sea holly. Husk of the emerald-green blister beetle known as the Spanish fly. So colourful and exotic is the list of substances that have been claimed to heighten sexual appetite that it is hard not to feel a twinge of disappointment on first beholding the latest entry - a small, white plastic nasal inhaler containing an odourless, colourless synthetic chemical called PT-141. Plain as it is, however, there is one thing that distinguishes PT-141 from the 4,000 years' worth of recorded medicinal aphrodisiacs that precede it: this one actually works.
    And it could reach the market in as little as three years. The full range of possible risks and side effects has yet to be determined, but already this much is known: a dose of PT-141 results, in most cases, in a stirring in the loins in as little as 15 minutes. Women, according to one set of results, feel 'genital warmth, tingling and throbbing', not to mention 'a strong desire to have sex'.

    Among men who have been tested with the drug more extensively, the data set is richer: 'With PT-141, you feel good,' reported anonymous patient 007: 'not only sexually aroused, you feel younger and more energetic.' According to another patient, 'It helped the libido. So you have the urge and the desire...' Tales of pharmaceutically induced sexual prowess among 58-year-olds are common enough in the age of the Little Blue Pill, but they don't typically involve quite so urgent a repertoire. Or, as patient 128 put it: 'My wife knows. She can tell the difference between Viagra and PT-141.'

    The precise mechanisms by which PT-141 does its job remain unclear, but the rough idea is this: where Viagra acts on the circulatory system, helping blood flow into the penis, PT-141 goes to the brain itself. 'It's not merely allowing a sexual response to take place more easily,' explains Michael A Perelman, co-director of the Human Sexuality Program at New York Presbyterian Hospital and a sexual-medicine adviser on the PT-141 trials. 'It may be having an effect, literally, on how we think and feel.'

    Palatin Technologies, the New Jersey-based maker of PT-141, has hopes of its own. Once the company gets Food and Drug Administration (FDA) approval for the drug, Palatin plans to market it to the same people targeted by Viagra: male erectile-dysfunction patients. Approval as a treatment for female sexual dysfunction may follow. In the wake of Pfizer's failed attempts to prove Viagra works for women and amid growing recognition that it also doesn't work for large numbers of men, these two markets alone could make PT-141 a pharmaceutical blockbuster.

    The market analysis was encouraging. As a late entrant in the market for erectile-dysfunction treatments, PT-141 stood a decent chance of mopping up the floor. By this stage in Viagra's life cycle, for instance, it was clear that the drug solved nothing for perhaps 50 per cent of impotent patients, either because their general health was too poor to risk Viagra's side effects or because it simply didn't work for them. But existing Viagra users weren't out of play either: PT-141 had a potential edge not just in ease of use, but in quality of results. ('On the five-point scale,' said patient 041, 'I would rate the erection I had as a six.') And there was a final and especially intriguing possibility: since PT-141 affects arousal through a different, more brain-centric mechanism than Viagra, might it work for women with sexual dysfunction?

    The testimony of rats - notwithstanding that of the 900 articulate, full-grown human subjects who have since reported enhanced arousal and desire from taking PT-141 - remains the most objective evaluation the drug has yet received, or ever will.

    'I see a lot of couples in my practice who don't know how to relax,' says Leonore Tiefer, a professor of psychiatry at New York University School of Medicine. 'That's fine - it's a big asset to them in their corporate lifestyle, where they can work 80 hours a week. They're trained to multi-task. Well, it doesn't seem that that is really doable when it comes to sex. And they're angry about that: they need it to be doable because they only have their five minutes.'

    Good things would come of it, to be sure. Marriages would be saved, fun would be had. But sexual Utopia? PT-141 seems just as likely to usher in the age of McNookie: quick, easy couplings low on emotional nutrition. Sex lives tailored to the demands of a jealous office or an impatient spouse. A dark age of erotic self-ignorance tarted up in the bright-coloured packaging of a Happy Meal.

  2. #2
    Lucky Seven's Avatar
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    McNookie sounds good to me. Is it on the value menu?

  3. #3
    Virginian's Avatar
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    It's basically me in a bottle lol Enjoy, fellas. hehe



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